THE ROY LAB
 
 

NRPS Research Lab

 
 
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Publications

1. The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Raktim N. Roy, Ivan B. Lomakin, Matthieu G. Gagnon & Thomas A. Steitz. Nature Structural & Molecular Biology. 22, 466–469 (2015)

https://www.nature.com/articles/nsmb.3031

2. Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Matthieu G. Gagnon, Raktim N. Roy, Ivan B. Lomakin, Tanja Florin, Alexander S. Mankin & Thomas A. Steitz. Nucleic Acids Research. 44, 2439–2450 (2016) 

https://academic.oup.com/nar/article/44/5/2439/2465042

3. Molecular Dynamics analysis of Mg2+-dependent cleavage of a Pistol Ribozyme reveals a fail-safe secondary Ion for catalysis. Raktim N. Roy, Newlyn N. Joseph & Thomas A. Steitz. Journal of Computational Chemistry. (2021)

https://doi.org/10.1002/jcc.26179

https://onlinelibrary.wiley.com/doi/full/10.1002/jcc.26179

4. pdbmine: A Node.js API for the RCSB Protein Data Bank (PDB). Newlyn N. Joseph, Raktim N. Roy & Thomas A. Steitz.

https://arxiv.org/pdf/1904.03801.pdf

 5. Structural Plasticity of the Selectivity Filter in a Nonselective Ion Channel.Raktim N. Roy, Kitty Hendriks, Wojciech Kopec, Saeid Abdolvand, Kevin L. Weiss, Bert L. de Groot, Adam Lange, Han Sun & Leighton Coates. IuCR-J. (2021)

https://journals.iucr.org/m/issues/2021/03/00/mf5049/

6. Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation. Dobeen Hwang, Napon Nilchan, HaJeung Park, Raktim N. Roy, William R. Roush, and Christoph Rader. Bioconjugate Chemistry. (2022)

https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.2c00146

7. Orphan receptor GPR158 serves as a metabotropic glycine receoptor:mGlyR. Thibaut Laboute, Stefano Zucca, Matthew Holcomb, Dipak N. Patil, Chris Garza, Brittany A. Wheatley, Raktim N. Roy, Stefano Forli, and Kirill A. Martemyanov. Science. (2023)

https://www.science.org/doi/full/10.1126/science.add7150


 
 
 
 

“Success is stumbling from failure to failure with no loss of enthusiasm.”

Sir Winston Churchill    

 
 
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